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Can Ciprofloxacin And Orhydrocodon Acetaminophn Cause False Positive Results?

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Posted on Thu, 16 Jan 2014
Question: i am looking for dr. vivck caile, he answered a question. i forgot to tell him the test's were done in a lab in arizona thru a drug rehab., is it possible that they could have made a mistake in there lab tests. he said that it is possible that the medication my wife was prescribed by her dr. could show a false positive . can you answere this for me again. the medication is CIPROFLOXACIN-HCL 250 MG, ORHYDROCODON-ACETAMINOPHN 10-325 and it showed a positive for methamphatmine. is this possible ???
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Answered by Dr. Vivek Chail (59 minutes later)
Brief Answer: Please find detailed answer below Detailed Answer: Hi XXXX, This is Dr.Vivek Chail replying to your question. Ciprofloxacin XXXXXXX 250 mg can cause false positive for opiates. Oxyhydrocodon Acetaminophen can cause false positive for methamphetamine. Urine drug screens are generally performed using either immunoassays or gas chromatography-mass spectrometry (GC-MS). Immunoassay urine drug screens (UDS) contain specific antibodies against common drugs of abuse and their metabolites. The immunoassay is the most commonly used UDS because it is inexpensive and rapid. Therefore, a more specific confirmatory test, such as GC-MS, is needed to confirm a positive finding with an immunoassay. GC-MS is more accurate than an immunoassay, but it is more expensive and time consuming. It is important that you let the lab facility know that your wife is on some medications for a while and that further confirmatory testing be done if felt necessary. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Vivek Chail

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Practicing since :2002

Answered : 6874 Questions

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Can Ciprofloxacin And Orhydrocodon Acetaminophn Cause False Positive Results?

Brief Answer: Please find detailed answer below Detailed Answer: Hi XXXX, This is Dr.Vivek Chail replying to your question. Ciprofloxacin XXXXXXX 250 mg can cause false positive for opiates. Oxyhydrocodon Acetaminophen can cause false positive for methamphetamine. Urine drug screens are generally performed using either immunoassays or gas chromatography-mass spectrometry (GC-MS). Immunoassay urine drug screens (UDS) contain specific antibodies against common drugs of abuse and their metabolites. The immunoassay is the most commonly used UDS because it is inexpensive and rapid. Therefore, a more specific confirmatory test, such as GC-MS, is needed to confirm a positive finding with an immunoassay. GC-MS is more accurate than an immunoassay, but it is more expensive and time consuming. It is important that you let the lab facility know that your wife is on some medications for a while and that further confirmatory testing be done if felt necessary. Hope your query is answered. Do write back if you have any doubts. Regards, Dr.Vivek