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Are Androgen Receptors Present At 0 To 6 Months Of Age?

Posted on Mon, 21 Oct 2013

Question: I have a question regarding androgen receptors and androgens.

1. Are androgen receptors present at age 0-6 months? Or is this question nonsensical because always present from fetal stage?

2. If present at age 0-6 months, does circulating androgens automatically bind to them, in ALL cells that they are found?

please help me with these questions. thank you

Regards,

Answered by Dr. Lohit K (2 hours later)

Brief Answer:
Present in fetal life. Yes will bind to cells

Detailed Answer:
Hi XXXXX, thanks for using XXXXXXX
I appreciate your curiosity in knowing the information.

Q1. Are androgen receptors present at age 0-6 months?
Yes. they are present before birth during fetal stage itself.

2. Does circulating androgen automatically bind to them, in all cells that they are found?
Yes. They will act on all the cells. But the receptor sensitivity and the actions differs at different organs.
The androgen bind to androgen receptors in cytoplasm and after binding they act in nucleus of the cell. They are responsible for primary and secondary male sexual characteristics and also growth and development in male.

Hope this answered your questions and is helpful for you.
Feel free to ask if any related query and I will be glad to answer them.

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Wish you a very happy life and good health.
Regards,

Wish you good health.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Lohit K (1 hour later)

Thank you for answer Dr Lohit K.

I understand androgen receptors are found in pituitary cells. Are they present even at 0-6 months age in baby boy?

I ask because at this age there a surge in testosterone.....does it bind to the pitutary cells even at this age, but perhaps with limited action?

Wishing you all the best.

Regards

Answered by Dr. Lohit K (16 hours later)

Brief Answer:
yes receptors are present and they act

Detailed Answer:
Hi XXXXX. Thanks for writing back.

Yes even at the age of 0-6months they have receptors and the testosterone will act. They help in growth, development and the growth of sex organs and the function.

Hope this explained your query. Feel free to ask if any query.
Wish you good health. Take care.
Regards

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar