Fentanyl Citrate
Parenteral. Preanesthetic medication, induction, and maintenance of anesthesia of short duration and immediate postoperative period. Supplement in general or regional anesthesia. Combined with droperidol for preanesthetic medication, induction of anesthesia, or as adjunct in maintenance of general or regional anesthesia. Combined with oxygen for anesthesia in high-risk clients undergoing open heart surgery, orthopedic procedures, or complicated neurologic procedures.
Oral (transmucosal). Anesthetic premedication in children and adults in an operating room setting. To induce conscious sedation before diagnostic or medical procedures (use only in closely monitored situations due to the risk of hypoventilation).
Pefloxacine
Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life threatening bacterial infections. Pefloxacin is commonly referred to as a fluoroquinolone (or quinolone ) drug and is a member of the fluoroquinolone class of antibacterials. It is an analog of norfloxacin . It is a synthetic fluoroquinolone, belonging to the 3rd generation of quinolones. Pefloxacin is extensively prescribed in France. ref New Milestones Achieved in Fluoroquinolone Safety Glenn S. Tillotson, M.Sc., FRSM, Public Health Research Institute, New York University, New York, New York; and Michael J. Rybak, Pharm.D., FCCP, Department of Pharmacy Services, The Anti-Infective Research Laboratory, and Detroit Receiving Hospital, Wayne State University, Detroit, Michigan http://www.medscape.com/viewarticle/409689 /ref Pefloxacin has not been approved for use in the United States. There are no licensed uses for Pefloxacin in the United States, as the FDA has not approved this drug. The licensed use varies in other countries and is quite limited as Pefloxacin is to be considered a drug of last resort when all other antibiotics have failed. There appears to be eight common uses in the adult population and no approved uses in the pediatric population, as well as a variety of veterinary uses (as documented within the package inserts). Pefloxacin interacts with a number of other drugs, a number of herbal and natural supplements, and certain thyroid medications.
Cimetidine
Treatment and maintenance of active duodenal ulcers. Short-term (6 weeks) treatment of benign gastric ulcers (in rare cases, healing has occurred). As part of multidrug regimen to eradicate Helicobacter pylori. Management of gastric acid hypersecretory states (Zollinger-Ellison syndrome, systemic mastocytosis). Gastroesophageal reflux disease, including erosive esophagitis. Prophylaxis of upper GI bleeding in critically ill hospitalized clients. Investigational: Prior to surgery to prevent aspiration pneumonitis, secondary hyperparathyroidism in chronic hemodialysis clients, prophylaxis of stress-induced ulcers, hyperparathyroidism, dyspepsia, herpes virus infections, tinea capitis, hirsute women, chronic idiopathic urticaria, dermatologic anaphylaxis, acetaminophen overdosage, warts, colorectal cancer.
OTC: Relief of symptoms of heartburn, acid indigestion, and sour stomach Treatment and maintenance of active duodenal ulcers. Short-term (6 weeks) treatment of benign gastric ulcers (in rare cases, healing has occurred).
As part of multidrug regimen to eradicate Helicobacter pylori.
Management of gastric acid hypersecretory states (Zollinger-Ellison syndrome, systemic mastocytosis).
Gastroesophageal reflux disease, including erosive esophagitis.
Prophylaxis of upper GI bleeding in critically ill hospitalized clients.
Investigational: Prior to surgery to prevent aspiration pneumonitis, secondary hyperparathyroidism in chronic hemodialysis clients, prophylaxis of stress-induced ulcers, hyperparathyroidism, dyspepsia, herpes virus infections, tinea capitis, hirsute women, chronic idiopathic urticaria, dermatologic anaphylaxis, acetaminophen overdosage, warts, colorectal cancer.
-Relief of symptoms of heartburn, acid indigestion, and sour stomach
Ofloxacin
Systemic: Pneumonia or acute bacterial exacerbations of chronic bronchitis or community-acquired pneumonia due to Haemophilus influenzae or Streptococcus pneumoniae. Not a drug of first choice in the treatment of presumed or confirmed pneumococcal pneumonia. Not effective for syphilis.
Acute, uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae; nongonococcal urethritis, and cervicitis due to Chlamydia trachomatis. Mixed infections of the urethra and cervix due to N. gonorrhoeae and C. trachomatis.
Mild to moderate skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, or Proteus mirabilis.
Uncomplicated cystitis due to Citrobacter diversus, Enterobacter aerogenes, E. coli, Klebsiella pneumoniae, Proteus mirabilis, or Pseudomonas aeruginosa. Complicated UTIs due to Escherichia coli, K. pneumoniae, P. mirabilis, C. diversus, or P. aeruginosa. Prostatitis due to E. coli.
IV therapy is indicated when the client is unable to take PO medication.
Ophthalmic: Treatment of conjunctivitis caused by S. aureus, Staphylococcus epidermidis, S. pneumoniae, Enterobacter cloacae, H. influenzae, P. mirabilis, and P. aeruginosa. Corneal ulcers caused by susceptible organisms Pneumonia or acute bacterial exacerbations of chronic bronchitis or community-acquired pneumonia due to Haemophilus influenzae or Streptococcus pneumoniae. Not a drug of first choice in the treatment of presumed or confirmed pneumococcal pneumonia. Not effective for syphilis.
Acute, uncomplicated urethral and cervical gonorrhea due to Neisseria gonorrhoeae; nongonococcal urethritis, and cervicitis due to Chlamydia trachomatis. Mixed infections of the urethra and cervix due to N. gonorrhoeae and C. trachomatis.
Mild to moderate skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, or Proteus mirabilis.
Uncomplicated cystitis due to Citrobacter diversus, Enterobacter aerogenes, E. coli, Klebsiella pneumoniae, Proteus mirabilis, or Pseudomonas aeruginosa. Complicated UTIs due to Escherichia coli, K. pneumoniae, P. mirabilis, C. diversus, or P. aeruginosa. Prostatitis due to E. coli.
IV therapy is indicated when the client is unable to take PO medication.
Ophthalmic: Treatment of conjunctivitis caused by S. aureus, Staphylococcus epidermidis, S. pneumoniae, Enterobacter cloacae, H. influenzae, P. mirabilis, and P. aeruginosa. Corneal ulcers caused by susceptible organisms