Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
198 Doctors are Online

Parathyroid hormone in osteoporosis - Online Doctor Chats

Date : 13-Jan-2012
User rating for this question
Excellent Posted in: General Health
Answered by

General & Family Physician
Practicing since : 2004
Answered : 1385 Questions
Doctor :   hi
User :   hello
Doctor :   how can i help you
User :   i have a question regarding PTH
Doctor :   age, gender
Doctor :   ok
User :   why in low doses can it be used for osteoporosis
User :   when it takes calcium out of the bone
Doctor :   pth is hormone is prscribed by any doctor to you
User :   no
User :   i just want to know how thats possible
Doctor :   it cannot be done, unless ure examined
User :   i dont need it
User :   im asking you how it can be used for treatment of osteoporosis
Doctor :   then is any one has osteoporsis
User :   if it takes calcium out of the bone and into the blood
User :   its doing research
User :   im doing research
Doctor :   ok, theotically it stabilises the blood calcium
User :   but wouldnt it take calcium out of the bone
Doctor :   but, osteoporosis is less calcium in bone
User :   ok
User :   so your saying with people who have osteoporosis
Doctor :   yes, it takes out,it will cause more porosis
User :   PTH has less osteoclastic activity
User :   so then if it takes it out
User :   how can pth in low doses be used for osteoporosis
Doctor :   pth has one more action, it decreases the excreation of calcium from kidney
Doctor :   so the blood calcium is stabilised
User :   ok
Doctor :   inturn it may help to deposit in the bone
Doctor :   so in very low doses it may help
User :   so when u have such bad osteoporosis, pth activates blast?
Doctor :   exactlly in low doses it may, to maintain the homeostasis
Doctor :   but ,i think its in research level
User :   ah
User :   ok
Doctor :   its not prescribed routinely
User :   then i have a question regarding etidronate
Doctor :   ok,intesting
User :   it (-) vit d3 formation i understand that, but doesnt vit D increase your calcitrial, and decrease your excretion, so how does that play a role with hyperparathroidism
User :   especially since the issue with hyperparathroidism is mainly pth
User :   just by the fact that you stop the increase in calcitrial from the pth action too?
Doctor :   calcitriol increses the excreation of calcium from the body
User :   i thought it increass the GI absorption
Doctor :   in hypertyriodism , calium is more in blood,so calcitrol is helpful
Doctor :   calcium is balanced by 3 mechanism
User :   but PTH as a whole, you release ca+2 from the bone, giving you the hypercalcemia, but you also increase it in the blood by increasing the absorption of it throught the GIT, isnt that done by calcitriol
Doctor :   one is absorption by gi, 2 nd by excreation by kidney,and dipositing or withdrawing from bone
User :   so the absorpton of it throught GI isnt that done through calcitrio
User :   and obviously the TAL
User :   in the kidneys
Doctor :   calcitiol does opposite action of pth and vit D
Doctor :   are you there
User :   but its a form of Vitamin D3
User :   It increases gastrointestinal calcium absorption, stimulates osteoclastic calcium resorption from bone, facilitates the effect parathyroid hormone
Doctor :   ok,
User :   so ok i guess ill skip that question, um then with regards to lactoferrin
User :   what role does that play with staph
Doctor :   but pth and calcitriol have opposite action
User :   sorry for these questions
User :   im in med school
User :   haha im not insane i promise
Doctor :   it has anti bacterial activiy,mainly found in milk
Doctor :   so it inhibits stap growth
Doctor :   thats nice, which year are you in
User :   finishing my second year
User :   doing micro, pharm, and path right now
User :   and path is really really hard
Doctor :   see we are disscusing, ok what i remmember i am telling you
Doctor :   what you want in path
Doctor :   which college are you in
User :   University of chicago
Doctor :   and calcium metabolism is very intersting and important for exams
User :   what kind of doctor are you?
Doctor :   i am a dermatologist
User :   thats very cool
Doctor :   ok, my memory of pharm is long remote one
User :   haha its ok
User :   you have been very helpful
Doctor :   tats ok, any time you can log in , any quires, all the best for your studies
User :   so question, this is a micro question do you ever deal with pseduomonas aeruginosa?
Doctor :   yes,
Doctor :   yes we get lot ofcases
User :   does it usually come from something like tinea pedis?
Doctor :   why
Doctor :   tenia is afungal infection
User :   yeah
User :   but can that be a secondary inection
User :   becuase of the pedis's skin damage?
Doctor :   it can be secondary after longterm use of antibiotics
User :   ok
User :   whats that alginate
User :   what is that
Doctor :   AAAAAAA this is Dr AAAAAAA here
User :   hi dr. AAAAAAA
Doctor :   i a skin specialist
Doctor :   please proceed
User :   i had a question, im in med school, and im studying pseudomonas aeruginosa
Doctor :   ok
User :   i was wondering if thats a common 2ndary form somthing like tinea pedis
Doctor :   i wil help u in this
Doctor :   Tinea pedis is a fungal infection of the toes and intertrigenous area
Doctor :   usaally occurs in the following induviduals
Doctor :   risk factors are
Doctor :   1. diabetes
Doctor :   2. patients on broad spectrum antibiotics
Doctor :   3. immunocompromised induviduals
Doctor :   like HIV and those on steroids and immunosupressives
Doctor :   4. and induviduals who spend more time in water
Doctor :   Psuedomonas is a bacteria
User :   yeah i know
User :   but can it be a possible secondary
Doctor :   which causes most of secondary
User :   ok
Doctor :   infection
User :   what is alginate
Doctor :   particulary in diabetics, alcoholic, and old age group
Doctor :   Alginate is gel or cellular material from brown algae
User :   does that develope from aeruginosa
Doctor :   no it is gel material from brown algea
Doctor :   it does not develop from aeruginosa
User :   so whats the mucoid exopolysaccharide slime from aeruginosa called
Doctor :   yes aeruginosa also produces alginate
User :   ok
Doctor :   plays a role in the adhesion of bacterium to epithelial cell surfaces
User :   ok
User :   does lactoferrin help with that
Doctor :   this alginate is also produced by other organsims
Doctor :   like acetobacter
User :   so they both have acetate in common
User :   is that why they both --> alginate
Doctor :   yes
Doctor :   you are right
User :   ok
User :   thank you very much dr.
Doctor :   lactoferrin
User :   doesnt that just take up the iron so that the bactieria cant utilize it?
Doctor :   Pseudomonas aeruginosa promoted when the strain was cultured in an iron-depleted succinate medium, supplemented with transferrin and lactoferrin iron-saturation.
Doctor :   Lower lactoferrin iron saturation (
Doctor :   so lactoferrin is essential ingredient for the growth of the bacteria
Doctor :   lactoferrin at 60% and 100% at iron-saturation is ideal for the growth of bacteria
Doctor :   are yu there??????
User :   i thought lactoferrin was somthing that inhibits the growth of bacteria
User :   it prevents the growth
User :   by stealing its iron
Doctor :   this is lactoferrin in relation to pseudomas
User :   ok
User :   gotcha
User :   what does the bacillus genus natural flora do for us?
User :   like where is it located
Doctor :   when yu take general lactoferrin is protein found in milk, colustrum, tears,
User :   the only bascillis i know is antrhax
Doctor :   and other secretions
User :   ok
Doctor :   which helps in defensive mechanism
Doctor :   its inhibits the adhesion of the bacteria and viruses to the host epitheilal cells
Doctor :   it has antibacterial, antiviral and antifungal activity
User :   ok
Doctor :   are yu taking about Lactobacillus
Doctor :   The most common application of Lactobacillus is industrial, specifically for dairy production.
User :   actually i guess that makes sense
User :   what about neisseria
Doctor :   Neisseria is gram postive cocci
User :   i thought it was grm -
Doctor :   wat yu want to know about Neisseria
User :   it can be natural flora also
User :   so is that a opertunisitic bacteria
User :   and if you have lower other flora
Doctor :   yes it can be normal flora in gential mucous membarne
User :   can give u gonorrhea
Doctor :   yes you are right AAAAAAA
Doctor :   it causes opputusinistic infection
User :   ok
Doctor :   when immune system is breached
User :   ok
User :   like on a steroid
Doctor :   steroids, immunosupressives, alchohol, bad vaginal hygeine
Doctor :   HIV and others
User :   and strep b
User :   isnt that seen in women
User :   vaginal
User :   is that from fecal to vaginal transmission?
Doctor :   Step B is common flora of mouth, skin, intestine and upper respiratory tract
Doctor :   so the vaginal transmission is not there
Doctor :   nor feco vaginal transmission
Doctor :   Strep. agalactiae is a species of the normal flora of the female urogenital tract and rectum.
Doctor :   transferred to a neonate passing through the birth canal and can cause serious group B streptococcal infection.
User :   but the b strepococci isnt seen in the vagina?
User :   of the baby or the mother
Doctor :   group A of beta hemolytic strep is Pharygitis, nephitis,
Doctor :   group B of beta hemolytic strep- agalactiae
Doctor :   S. agalactiae is a major cause of bacterial septicemia of the newborn
User :   ok
Doctor :   neonatal meningitis
User :   so therefore when you said that strep agalactia is see in the rectum
User :   and thats a type b
Doctor :   group c of beta hemolytic strep
User :   that had to have been transmitted fecal to vaginal
Doctor :   is Equi
Doctor :   it infects cattle and horses
User :   hence the baby getting it from delivery
User :   right?
Doctor :   its vaginal and rectum
User :   ok
User :   so its not from the rectum to the vagina
Doctor :   mainly female urogenital tract
User :   they both have it
User :   ok
Doctor :   transferred to a neonate through the birth canal
User :   so do women (post menapausal) have a higher right of vaginal infections
Doctor :   yes post menopausal women has high risk for vaginal infection
Doctor :   due
Doctor :   1. senile vaginaitis
User :   to the flora that requires estrogen
Doctor :   2. loss of estrogen
User :   the lactobacillis
Doctor :   3. loss of normal flora like doderline bacillus
User :   can u get q fever from rickettsia
Doctor :   Yes yu get fever from Rickettsia
Doctor :   A self limiting condition that is transmitted by mites
Doctor :   it causes
Doctor :   1. R. typhus
Doctor :   2. Q fever
User :   rocky mountain spotted fever?
Doctor :   3. Rocky mountain spotted fever
User :   cool
User :   what is psittacosis
Doctor :   Rocky mountain spotted fever - Rikecttsia rickettsie
Doctor :   psittacosis - chlamydia psittachai
User :   can u treat that with tetracycline?
Doctor :   its also called parrot fever, spreads by bird dropping
User :   but that a bacteriostatic
User :   would that suffice?
Doctor :   treat ment is Tetracycline
Doctor :   Doxycycline
User :   what about chloramphenicol
Doctor :   Ricketssia and chlamydia does not respond to other antibioitic
Doctor :   chloramphenicol can be used but has more side effects on bone marrow
Doctor :   so ideal is to go for Doxycyline
User :   what about neomycin
User :   or gentamicin
User :   less toxic
User :   but then theres the cn8 issues
Doctor :   Its a gut antibiotic
User :   then how about macrolides
Doctor :   the mechanism of action of tetracycyline
User :   like a erythromycin
Doctor :   inhibit bacterial protein synthesis by blocking the attachment of the transfer RNA-amino acid to the ribosome.
User :   ok
User :   if you had toxoplasma dondill
Doctor :   so tetracyclines can penetarate the chlymadia and rickettisa
User :   would azithromycin work?
User :   gontil*
User :   gondil*
Doctor :   yes toxoplama - azithromycin or macrolides
Doctor :   but pregnancy - its spiramycin the drug of choice
User :   now what about linezolids
User :   for MRSA?
Doctor :   Linezolids are used if vancomycin is resistant
Doctor :   For MRSA vancomycin is the drug of choice
Doctor :   but if vancomycin is resistant then go for
User :   can you have VMRSA
Doctor :   linezolid
User :   ok
Doctor :   Quinopristone
Doctor :   Dalfipristone
User :   what about rifampicin'
User :   just for TB?
Doctor :   ideal drug for tubeculosis its bactericidal
User :   what about the wierd sweat color'
User :   is that dangerous
Doctor :   useful in acitve and rapid growers
Doctor :   has few side effects
Doctor :   like respiratory flu like
Doctor :   abdominal flu like
User :   you sweat orange
Doctor :   orange color urine
User :   ok
Doctor :   and hepatotoxic
Doctor :   dose need to be adjusted
User :   when would u use a trimethoprim
Doctor :   based on hepatotoxicity
Doctor :   ideal drug for Pnemocystis carinii pneumonia
User :   does that inhibit folic acid sythn?
Doctor :   bacterial dihydrofolate reductase (folate antagonist)
User :   ok
Doctor :   Please fill the feed back form
User :   i did
User :   thank you very much
Doctor :   thank you
User :   i really appreciate it
User :   sorry if i drove you crazy
Doctor :   Is there any thing else i can help u with
User :   no
Doctor :   no need for sorry
Doctor :   i have cleared your doubts AAAAAAA
User :   yes you have
Doctor :   its my pleasure and duty
User :   take care
Doctor :   ok take care bye for now
User :   bye
User :   whats ur name
User :   so i can request you
Doctor :   Me dr xxxx
User :   ok
User :   are you on alot or can i just ask for you?
Doctor :   yu can ask for me
User :   ok
Doctor :   there are also other doctors
User :   thank you Dr xxxx
User :   yes but you really know your stuff
Doctor :   working with me
Doctor :   ok
Doctor :   take care
Doctor :   Thanks for consulting Health care magic. Take care bye for now. Please refer your friends
Question is related to
Diseases and Conditions
Medical Topics
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor