ICSI is intra-cytoplasmic sperm injection, newest fertility technique. ICSI method is used as in your case when infertility is mostly due to male sperm issues.ICSI is a very effective method to get fertilization of eggs in the In-vitro fertilization lab after they have been retrieved from the female partner. ICSI involves the use of specialized micromanipulation tools and equipment and inverted microscopes that enable embryologists to select and then pick up individual sperms in a tiny specially designed hollow ICSI needle. Then the needle is carefully advanced through the outer shell of the egg and egg membrane and the sperm is then injected into the inner part (cytoplasm) of the egg. This will usually result in normal fertilization in approximately 70-85% of eggs injected with viable sperm. First, the woman must be stimulated with medications and have an egg retrieval procedure so that we can obtain several eggs in order to attempt in vitro fertilization and ICSI.ICSI differs from In-vitro fertilization, wherein one egg is mixed with 1 lakh sperms, with fertilization taking place on its own, ICSI is a technique where each egg is held and injected with a single live sperm. This micro-fertilization is done with the help of a machine called the Micromanipulator. Pregnancy success rates for in vitro fertilization procedures with ICSI have been shown in some studies to be higher than for In-Vitro Fertilization without ICSI.